If you are looking for a comprehensive, non-surgical treatment that restores radiance, improves hydration, and stimulates deep regeneration, our Totally Regenerative Microneedling protocol may be the perfect solution.
This powerful 90-minute skin rejuvenation treatment is designed to stimulate renewal from multiple angles. This advanced protocol combines the precision of medical microneedling with the regenerative benefits of polynucleotides, niacinamide, and hyaluronic acid skin booster injections, followed by a soothing LED diode laser mask to support recovery and enhance glow.
Results are typically visible within a few days and continue to improve as collagen and elastin production increase over the following weeks.
Minimal downtime. Most clients can expect 24 to 48 hours of mild redness, depending on skin sensitivity.
For best results, a course of 3 sessions is recommended, spaced 4 to 6 weeks apart.
The totally regenerative microneedling is ideal for clients seeking to improve skin quality, hydration, texture, radiance, and overall rejuvenation, with a protocol that works both on the surface and within the skin. By combining microneedling with targeted regenerative ingredients and LED light therapy, we achieve results that go far beyond what a single approach can deliver.
The microneedling step primes the skin, allowing polynucleotides, natural DNA fragments that stimulate fibroblast activity, to penetrate deeply. Niacinamide (vitamin B3) soothes inflammation and evens tone, while hyaluronic acid skin boosters infuse the dermis with long-lasting moisture. The finishing LED mask uses specific wavelengths to reduce redness and accelerate healing, meaning you leave the clinic already glowing.
Whether your goals are improved texture, a hydrated, plump look, or overall rejuvenation, this protocol delivers noticeable, layered results with minimal downtime.
What this treatment includes
Your skin will be thoroughly cleansed. The medical-grade microneedling pen is then used to create controlled microchannels through which polynucleotides and niacinamide are infused.
Following this, hyaluronic acid skin-booster injections are administered in key areas to provide deep hydration. The session concludes with a 10-minute LED diode laser mask to calm the skin and boost cellular repair. The entire treatment takes approximately 90 minutes.
Your skin may appear flushed or slightly red, like a mild sunburn, for 24–48 hours. Avoid touching your face for at least 24 hours. Use a gentle cleanser and apply the post-procedure skincare recommended by your practitioner.
It is essential to use a broad-spectrum sunscreen of SPF 30 or higher daily. Avoid strenuous exercise, saunas, and swimming for 48 hours to minimise irritation.
Most clients notice an immediate glow and a plumping effect after the treatment. Over the following days, skin texture becomes smoother, and hydration levels increase.
Full regenerative benefits develop over 4–6 weeks as collagen remodelling continues. A course of 3 sessions, spaced 4–6 weeks apart, is typically recommended for optimal, long-lasting results.
Your skin will be thoroughly cleansed. The medical-grade microneedling pen is then used to create controlled microchannels through which polynucleotides and niacinamide are infused.
Following this, hyaluronic acid skin-booster injections are administered in key areas to provide deep hydration. The session concludes with a 10-minute LED diode laser mask to calm the skin and boost cellular repair. The entire treatment takes approximately 90 minutes.
Your skin may appear flushed or slightly red, like a mild sunburn, for 24–48 hours. Avoid touching your face for at least 24 hours. Use a gentle cleanser and apply the post-procedure skincare recommended by your practitioner.
It is essential to use a broad-spectrum sunscreen of SPF 30 or higher daily. Avoid strenuous exercise, saunas, and swimming for 48 hours to minimise irritation.
Most clients notice an immediate glow and a plumping effect after the treatment. Over the following days, skin texture becomes smoother, and hydration levels increase.
Full regenerative benefits develop over 4–6 weeks as collagen remodelling continues. A course of 3 sessions, spaced 4–6 weeks apart, is typically recommended for optimal, long-lasting results.
EXCELLENT Based on 108 reviews Posted on Sam KavanaghTrustindex verifies that the original source of the review is Google. Cannot rate this clinic highly enough. From initial booking and greeting from Carly who is always so lovely and accommodating, through to the treatment with Flavio. I wouldn’t trust anyone else with my face. He takes time and pride in his procedures. He makes you feel so special as a patient, he shares advice, he makes you feel safe and talks through everything with you. You leave feeling so confident in your appearance. Flavio’s work is unmatched, truly an artist and a magician.Posted on hema sonejiTrustindex verifies that the original source of the review is Google. Oh my word, what an incredibly efficient and friendly place. Forgot my B12 while travelling and I was sorted within a day. Staff are just incrediblePosted on Olivia DaviesTrustindex verifies that the original source of the review is Google. Lovely welcoming clinic,Carly and Marina are fabulous, and I always feel like I am given the best service. I will be back for more treatments soonPosted on SarahTrustindex verifies that the original source of the review is Google. I had a fabulous deep cleanse facial by Marina and it was spectacular. Amazing results and just what I needed at the end of a holiday! I’ve been to the clinic on a few occasions for this facial and each time it has been the best! It is the only clinic I will go to for a deep cleanse facial as it has demonstrated better results than any other clinic I’ve been to. Marina did my first ever facial at CF so I was thrilled to have another appointment with her! I really appreciated the time and care she put into my facial. I love how the extraction process doesn’t cause much redness, so when you are leaving the clinic your face isn’t blotchy or painful.Posted on Jason MolloyTrustindex verifies that the original source of the review is Google. I’ve been coming to clinica Flore for a few years now and I honestly couldn’t recommended them enough. Always a warm welcome from the team Carly and Marina. The treatment is thoroughly professional and sorts out my chronic rosacea everytime, it’s a 10 out of 10 from me.Posted on Omphile maboTrustindex verifies that the original source of the review is Google. Before going in for my HIFU treatment I did some reading about the procedure, particularly about the side effects. One that had me a bit worried was being blotchy and red as I do have sensitive skin. However, Flavio was so gentle that I didn’t experience any redness after the treatment or pain during the procedure. Their staff is so friendly from the minute you call them to book an appointment to them performing the procedure. They update you with every step of the process so that you are aware of what they are doing to your face. I highly recommend their services they have indeed impressed me and I can’t wait for my next appointment with them. #HappyClientPosted on Franko BrisenoTrustindex verifies that the original source of the review is Google. I have been to other clinics and it is the first time the staff has been amazing, they showed they are actually passionate for what they do and they do care for the patients. I am over the moon with the treatments I received, I can say I’ve got incredible results. Definitely going back to Fiore for future treatments, and highly recommend it. Thank you so much Flavio, truly appreciate your commitment!Posted on FabriTrustindex verifies that the original source of the review is Google. Great combination of the new and improved HIFU and new skin pen with ultrasound! Both treatments combined have massively improved the skin texture and lifting of facial contours, not even 24 downtime and virtually painless in my case, loved it! Would definitely recommend this combo or even as separate treatments as I did see big improvements on each session! Also the clinic is always at such high standards and always immaculately presented! Thank you, will be back!Verified by TrustindexTrustindex verified badge is the Universal Symbol of Trust. Only the greatest companies can get the verified badge who has a review score above 4.5, based on customer reviews over the past 12 months. Read more
Yes. The inclusion of niacinamide and the finishing LED mask helps calm inflammation, making this protocol well tolerated by many clients with sensitive skin.
Your practitioner will assess your skin during the consultation to ensure it is appropriate for you.
You will notice an immediate glow and a hydrated, plumped appearance right after the treatment. Over the next few days, skin texture improves, and the full regenerative effects become visible within 4–6 weeks as collagen and elastin production increases.
For best results, a course of 3 sessions is recommended, spaced 4–6 weeks apart. Your practitioner will tailor a plan based on your skin concerns and goals.
Totally Regenerative Microneedling is designed as a comprehensive standalone protocol, but it can be part of a broader treatment plan. During your consultation, we can advise on the ideal sequencing with other services to maximise your results.
You can experience the Totally Regenerative Microneedling treatment at our clinic in Covent Garden, London.
Our expert team is dedicated to providing personalised care and ensuring you achieve the best results. Give us a call today to schedule your appointment. We look forward to welcoming you to our clinic!
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